Izizathu Ezintathu Zokungakhathazeki Nge-LDL Yakho
Nakuba izinkomba eziningi zezempilo zivame ukuthuthukisa ukudla okuncane (i- triglycerides , i-HDL cholesterol, i-glucose yegazi, umfutho wegazi, isisindo / isibalo se-hip, njll), umthelela we-carb low ekudleni kwe-LDL cholesterol iyinto eguquguqukayo, abantu behlehliswa futhi abanye banda. Abanye abantu bayethusa uma bebona ukuthi ukuphakama kwenombolo, kuyilapho odokotela babo bezama ukuthola isimiso somthetho.
Kodwa kukhona okungenani izizathu ezintathu zokuthatha umoya ojulile ngaphambi kokuthatha isinyathelo esengeziwe.
Iyini i-Cholesterol?
I-cholesterol ingumuthi we-waxy ohlobene namafutha. Nakuba i-LDL i-cholesterol ivame ukubizwa ngokuthi "kubi", ngicabanga kubalulekile ukuqonda ukuthi i-cholesterol, ngaphakathi kwayo, ayiyona into embi - eqinisweni, kuyadingeka ukuba imizimba yethu isebenze. Akukwenqabeli icala lokuthi sizofa ngaphandle kwe-cholesterol. I-cholesterol iyingxenye yamangqamuzana ethu esitokisini nomgogodla we-myelin ukuvikela izinhlelo zethu zezinzwa. Ibuye isetshenziswe ekwenzeni amahomoni amaningi (njenge-estrogen ne-testosterone), i-vitamin D, izinto ezibalulekile ekugayeni, nokunye okuningi. Imizimba yethu ikhiqiza i-cholesterol - kuye ngokwemikhuba yethu yokudla, noma yikuphi okuvela ku-80-100% we-cholesterol emizimbeni yethu kwenziwa "endlini".
Kuyini i-LDL Cholesterol Nalokho Okubi Kangako?
Kuvame ukukhuluma ngezinhlobo ezahlukene ze-cholesterol, kodwa lokhu akulona kahle.
Wonke ama-molecule we-cholesterol afana ncamashi; kuba nje ukuthi bahlanganiswe ngezindlela ezahlukene zokuthuthwa ngegazi lethu. "Isakhiwo sokuthutha" sibizwa nge-lipoprotein. I-HDL ifushane "ye-high-density lipoprotein" futhi ngezinye izikhathi ibizwa ngokuthi "i-cholesterol enhle". I-LDL ifushane "ye-low-density lipoprotein" futhi ivame ukubizwa ngokuthi "i-cholesterol embi".
(Kukhona ingxenye yesithathu, okuthiwa i-VLDL "ye-low-density lipoprotein", okuthiwa "i-cholesterol eyingozi kakhulu," kodwa kuncane kakhulu kwayo.) YiLDL ehambisana kakhulu nesifo senhliziyo esithinta ama-plaque emithanjeni.
Kodwa linda, kukhona okuningi! I-HDL ne-LDL zombili zihlukaniswa ngezigaba ezahlukene, futhi okuningi kutholakala mayelana "nezigaba" ezihlukene ngaphakathi kwezigaba "ze-lipoproteins. Endabeni ye-LDL, umehluko omkhulu kulezi zinhlobo ubukhulu nobukhulu bezinhlayiya ze-LDL. Abantu abaningi baye babonisa ukuthi inani le-LDL eliphelele akuyona yonke into enhle ekubikezele ukuthi ubani ozoqhubeka nokuthola isifo senhliziyo, kodwa ukutholakala kwamaphetheni usayizi wezinhlayiya kunikeze odokotela ulwazi oluningi mayelana nokuthi kuyingozi kangakanani i-LDL ethile umuntu ukhona. Kodwa okuningi ngalokho ku # 2 ngezansi - okokuqala ngifuna ukukhuluma kafushane:
1. Ukuphakama kwe-LDL kuvamise okwesikhashana
Kube khona izifundo ezimbalwa manje ezilandelela i-LDL ekudleni okuphansi kwe-carb. Kwezinye zazo, kukhona ukuthambekela kwabanye abantu ukuthi bakhulise i-LDL ezinyangeni ezingu-3-4, kepha ngenyanga ka-6 noma ngo-8, kubuyele emuva. Ngizwile izindaba eziningi ngalezi zindlela kusuka ezihlahleni eziphansi. Ngakho kubonakala kunengqondo ukugcina isandla sakho sisuse inkinobho yokuphazamiseka ezinyangeni zokuqala zohlelo lwakho lokudla oluphansi.
(Isizathu salo mkhuba, njengoba nje ngiyazi, asikwazi, kodwa kuye kwaphakanyiswa ukuthi i-cholesterol encibilikile emaqenjini amafutha angakhululwa emsakazweni wegazi ngesikhathi sokulahlekelwa kwesisindo, futhi ingabonakala ngokuphawulekayo ezinyangeni ezimbalwa zokuqala lapho ukulahlekelwa isisindo ngokushesha kakhulu.)
2. Ama-Patterns Amathrekhi Wezinhlayiyana Ngokujwayelekile Amathuthukisa Ekudleni Okuphansi-I-Carb
Ngakho kungani sikhathalela ngobukhulu bezinhlayiya ze-LDL? Kuvela ukuthi uma unezincani ezincane kakhulu, izinhlayiya ezincane ze-LDL (okuthiwa i-Pattern B), ukubikezela okuningi kwe-coronary artery sifo lapho izinhlayiya zinkulu futhi zingaphansi kakhulu (i-Pattern A).
Kuzo zonke izifundo ngiyazazi ukuthi kwakubheka usayizi wezinhlayiyana ze-LDL lapho abantu beshintshela ekudleni okuphansi kwe-carb, amaphethini ashintshiwe esiqondisweni esihle.
Kungani izinhlayiya ezinkulu kakhulu ziphephile? Ngezwa umfanekiso othakazelisayo ngumlobi uDkt. Mark Houston (uzwe lo mbuzo lapha - kusukela ngo-Agasti 25, 2012, umbukiso othi "Buza uDkt Dawn"). Wachaza ukuthi kunokuba umqondo ovamile we-cholesterol uvele uwakha ngaphakathi ngaphakathi komthambo, empeleni uqala ungqimba lomthambo ngaphansi kwe-epithelium (efana nesikhumba "somshini") uma kunomonakalo nokuvuvukala epithelium.
I-cholesterol (noma, ngokunembile, i-lipoprotein) izinhlayiya ezivela egazini bese zifaka kule ngqimba engaphansi kwe-epithelial futhi zakha kusuka lapho ukuze zenze i-plaque. Njengoba ikhula, i-plaque iqala ukuvimba umthambo. Lapho echaza umphumela wezinhlayiyana zezinhlayiya, uDkt. Houston wanikeza lo mfanekiso: Cabanga ngenetha enkantolo yezintambo. Ibhola le-tennis ngeke lihambe ngaleyo netha, kodwa uma uphonsa ibhola legalofu kulelo net, ezinye zazo zizoqhubeka. Lokhu kunikeza umbono onzima wokucabanga ukuthi kungani izinhlayiya ezincane ezinama-LDL ezinobungozi ziyingozi kakhulu kunezinhlayiya ezinkulu, "ama-fluffier" - amancane, anzima kakhulu angene endaweni ewonakele yomthamo. (UDkt. Houston uthi futhi inani lezinhlayiya ze-LDL lingabalulekile.)
Ngeke ukwazi ukuthola izinhlayiya ze-LDL kuhlolo olujwayelekile lwe-cholesterol. Udokotela wakho kuzodingeka ahlele ukuhlolwa okukhethekile. Lezi yizona ezimbili ezivame kakhulu:
- I-Auto-Profile yangempela (VAP)
- IGeldient Gel Electrophoresis (GGE)
3. I-LDL Ngokuvamile ayilinganiswanga ngokuqondile, okungahle kube yinkinga
Kuvela ukuthi kunzima ukulinganisa i-LDL ngokuqondile, ngakho ama-labs ngokuvamile asebenzisa ifomula ukulinganisa i-LDL kwezinye izinyathelo zegazi. Ibizwa ngokuthi i-Equation Friedewald futhi yilokhu: LDL = I-Total Cholesterol - HDL - (Triglycerides / 5). Kubantu abaningi, leli fomula linembile kakhulu, nakuba inhlanhla yematheksthi izobona ukuthi enye indlela "yokuthuthukisa" isikolo sakho se-LDL kuyoba ukumane ukhulise i-triglyceride yakho, isibonelo, idla ishukela. (Akusilo umqondo omuhle !! Lokhu nje ukukhomba inkinga engenzeka.) Manje, kwaziwa ukuthi uma i-triglycerides iphezulu kakhulu (ngaphezu kuka-400 mg / dL) ukulingana akukhiqizi imiphumela enembile. Kodwa kukhona nokusola okukhulayo ukuthi uma i-triglycerides ingavamile LOW (ngaphansi kwekhulu) i-LDL ingase ihlolwe ngokusebenzisa leli fomula. Kube khona izifundo ezimbalwa ngalokhu, futhi libika kusuka odokotela abasebenzisa imingcele ye-carbohydrate njengengxenye yokwelashwa kwabo kokukhuluphala nesifo sikashukela. Abantu abakudla ukudla okuncane okulandela ukudla bahlale bethola ukuthi ama-triglycerides abo awela phansi ezingaphansi kuka-100 (okungenani udokotela oyedwa, uDkt. Mary Vernon, usebenzisa i- triglycerides njengenye yezimpawu zokumtshela ukuthi isiguli silandela ukudla ). Ngakho uma i-triglycerides iphansi futhi i-LDL iphakeme, kungaba umqondo omuhle ukucela ukuhlolwa okulinganisa i-LDL ngokuqondile esikhundleni sokusebenzisa ifomu le-Friedewald.
Omunye wamaqembu afunde lokhu (Ahmadi et al) usethuthukise ukulingana okuhlukile, okuvame ukubizwa ngokuthi ukulingana kwe-Iranian. Yize kubalulekile ukuqaphela ukuthi lokhu kulingana akuvunyelwanga kabanzi emphakathini wezokwelapha wase-US, kungaba okuthakazelisayo ukuqhathanisa i-LDL yakho-etholakala ngama-equations ahlukene.
Ngokuthakazelisayo, ukuba ne-triglycerides ngaphansi kwezingu-100 kuhambelana nosayizi we-Pattern A LDL we-particle (iphethini enempilo). Ngakho-ke uma ulandela ukudla okuphansi-carb futhi une-triglycerides ephansi, kunezizathu ezimbili zokungakhathazeki okuningi nge-cholestol yakho ye-LDL, okungenani uze uthole ukuhlolwa okwengeziwe.
Imithombo:
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