Funda nge-endorphins nomthelela wabo emzimbeni
I-endorphins ivame ukubizwa ngokuthi ubuhlungu bomzimba bomzimba. I-Endorphins yizinto eziphilayo eziphilayo ezenziwe ngumzimba ezinciphisa ubuhlungu futhi zenze umuzwa wokujabula nokuphila kahle.
Ukuhlukaniswa kwama-Endorphin
Ama-endorphin ahlukaniswa ngokuthi "ama-popeptide opioid endogen" futhi acatshangwa ukuthi akhiqizwa i-pituitary gland ne-hypothalamus ngesikhathi sokuvivinya umzimba, futhi ephendula ubuhlungu, injabulo nezinye izinto ezicindezelayo.
Uma sekukhiqizwa, i-endorphins isakazwa kuyo yonke isimiso sezinzwa lapho ihlangana khona ne-opiate receptors ukunciphisa ukuqonda kwethu ubuhlungu. Lezi zinhlungu zemvelo ziyancipha nje ukunciphisa umbono wezinhlungu, kodwa nazo zihlobene nomqondo okhudlwana wokujabula nokuphila kahle.
Umlando we-Endorphins
Ama-Endorphins athola kuqala ngo-1974 ngamaqembu amabili ahlukene abaphenyi abazimele. Ama-Endorphins atholakala ngokusebenzisa nokutadisha ubuchopho bezilwane. Ososayensi uJohn Hughes noHans Kosterliltz, bobabili baseScotland, ama-endorphin aqala ukuhlukaniswa futhi ahlukanisiwe avela ebuchosheni bezingulube. Ngesikhathi esifanayo, uRabi Simantou noSoloman Snyder, bobabili base-United States, bahlonipha i-endorphins ebuchosheni bezinyane. Kwaphinde kwatholakala ukuthi umzimba womuntu, kanye nomzimba wezilwane eziningi, uyakwazi ukukhiqiza i-morphine ngokwayo.
Imiphumela yalolu cwaningo oluthile lunike amandla ososayensi bezinkanyezi ukuze banqume ukuthi ubuchopho bomuntu buqukethe i-endorphins ukukhawulela ubuhlungu, okuyinto i-pituitary ekhishwa lapho umzimba ungaphansi kokucindezeleka okukhulu, noma ukuzwa ubuhlungu obukhulu.
Lawa ma-endorphins asebenzisana nama-receptors ukunciphisa umbono jikelele wezinhlungu. Imiphumela yale nqubo iyalingiswa, ngakho-ke kufana nokusetshenziswa kwesidakamizwa esifana ne-morphine. Ngakho-ke, uma i-painkiller yokufakelwa efana ne-morphine ingeniswa emzimbeni, ngethemba lokuthi udokotela, unomphumela kuma-endorphin ajwayelekile ngokwemvelo.
Njengoba i-painkiller isetshenziselwa, ithola ubuningi bokuthola ubuhlungu bobuchopho. Umzimba uzwa lokhu, futhi ngokuphindaphindiwe, ukukhiqizwa kobuhlungu obuncane ngokweqile kukhishwa. Lokhu kuyindlela yokulinganisela yomzimba. Kodwa-ke, uma umthombo wokufakelwa ususiwe, izimpendulo eziningi zobuhlungu ziba yize. Lokhu kubangela ukulangazelela i-endorphins, ngokuvamile efana nama-narcotics, futhi lokhu kungukuthi umlutha ungaqala kanjani.
I-Runner's High
Kubantu abathile, ukugijima ibanga elide kakhulu kungabangela ukuzwa kanye nomqondo wokuzijabulisa oqhathaniswa nokuphakama okuphezulu okunikezwa izidakamizwa. Ukuzizwa okubikiwe kwalokhu kumgijimi kufaka phakathi: imizwa yokuthula okukhulu, ukuzwa okujulisayo, ukujabula, ukuvuselela, nokwehliswa ukubekezelela ubuhlungu.
Lo mgijimi uphakanyiswe izinga eliphakeme lama-endorphin ebuchosheni. Ama-endorphins akhululwa njalo emzimbeni njengomuntu ogijima ngabanye futhi ekugcineni, lokhu kuvuka kuma-endorphin ebuchosheni kuholela ekuzizweni kokujabula.
Umthombo:
Boecker, H., Sprenger, T., Spilker, ME, Henriksen, G., Koppenhoefer, M., Wagner, KJ, Valet, M., Berthele, A., Tolle, TR (2008). I-Runner's High: Izindlela ze-opioidergic ku-Human Brain. I-Cerebral Cortex DOI: 10.1093 / i-cercor / bhn013