Ama-amino acid we-branched-chain awuhlobo lwe-amino acid ebalulekile ekuhiqizweni komzimba wamaprotheni. Itholakala ekudleni okuningana (kuhlanganise inyama, imikhiqizo yobisi, kanye nemifino), ama-amino acids ane-branched ahlanganisa i-valine, i-leucine, ne-isoleucine. Wathi ukunikeza izinhlobonhlobo zezinzuzo zempilo nokuthuthukisa ukusebenza kwezemidlalo , ama-amino acid branched-chain nawo athengiswa ngefomu lokufakazela.
Ukusetshenziswa
Ngaphandle kokuthuthukisa ukusebenza kwezemidlalo, kwezinye izindlela zokwelapha, i-branched-chain chain amino acid kuthiwa ukusiza noma ukuvimbela izimo zempilo ezilandelayo:
- i-amyotrophic lateral sclerosis (eyaziwa nangokuthi isifo sikaLou Gehrig)
- isifo sikashukela
- isifo sesibindi
- Isifo sikaMcArdle
- ukuguqulwa kwe-spinocerebellar
- i-tardive dyskinesia
Ama-amino acid asetshenziselwa ukuhlanganiswa nawo asetshenziselwa ukuvimbela ukukhathala, ukuthuthukisa ukusebenza kobuchopho nokuhlushwa, ukugqugquzela ukulahlekelwa kwesisindo , nokugqugquzela ukondla kubantu abakwelashwa ngomdlavuza.
Izinzuzo
Ucwaningo oluningi lwezesayensi lubonisa ukuthi ukusetshenziswa kwezidakamizwa eziqukethe i-branched-chain chain amino acid kunganikeza izinzuzo ezithile zezempilo. Nakhu ukubuka ezinye izihluthulelo ezisemqoka ezivela ocwaningweni olutholakalayo:
1) Izifo zesibindi
I-amino acids yama-branched-chain angabasiza abanye abantu abanezifo zesibindi, ngokusho kocwaningo lwango-2011 olwanyatheliswa kuyi- Journal of Cellular Biochemistry . Ekuhlolweni kwamagundane, abacwaningi bathola ukuthi ama-branched-amino acids angasiza ekuvikeleni ukungahambi kahle kwe-sugar metabolism egazini ngokuvamile ehlotshaniswa ne-cirrhosis (isifo esibhalwe ngokunqunywa kwesibindi).
2) Ukusebenza kokuzivocavoca
Ucwaningo oluthile lubonisa ukuthi ukusebenzisa ama-amino acid we-branched kungathinta ukusebenza komsebenzi. Ngombiko wango-2006 oshicilelwe kuyi- Journal of Nutrition , isibonelo, abacwaningi bahlaziya ucwaningo olutholakalayo ekusetshenzisweni kwama-amino acid we-branched futhi bathola ukuthi izithako zingasiza ekuthuthukiseni ukusebenza komzimba nokuvimbela ukukhathala ngesikhathi sokuzivocavoca.
Kukhona nobufakazi bokuthi ama-amino acids ahlanganiswe ngamakhansela angasiza ekukhuthazeni ukuvuselelwa kwemisipha nokunciphisa ubuhlungu emva kokuzivocavoca. Isibonelo, isifundo se-2007 eshicilelwe kuyi- Journal of Sports Medicine and Physical Fitness sathola ukuthi ukusetshenziswa kwesiphuzo okuqukethe i-branched chain chain-amino acid kwasiza ukunciphisa izinga lokulimala kwemisipha kubagijimi abade kakhulu. Ekuhlolweni okubandakanya abagijimi abayisishiyagalombili, abalobi bezocwaningo bathola ukuthi isiphuzo se-branched-chain-amino-acid esiphundu siphumelele kakhulu kunesiphuzo se-placebo ekunciphiseni ukukhululwa kwe-lactate dehydrogenase (umaka wokulimala kwamathambo) ngesikhathi sekhilomitha eyi-25 run.
Amapulangwe
Izithako eziqukethe i-branched chain chain-amino acid zihambisana nemiphumela emibi eminingana, njengokukhathala nokulahlekelwa kwezimoto.
Khumbula ukuthi ama-supplements awazange ahlolwe ukuphepha kanye nezindleko zokudla ngokuyinhloko ezingavunyelwe ngokomthetho. Kwezinye izimo, umkhiqizo ungase ulethe ukulinganisa okungafani nesilinganiso esicacisiwe semifino ngayinye. Kwezinye izimo, umkhiqizo ungangcoliswa nezinye izinto ezifana nezensimbi. Futhi, ukuphepha kwezidakamizwa kwabesifazane abakhulelwe, omama abahlengikazi, izingane, nalabo abanezimo zezokwelapha noma abaphuza imishanguzo azange zisungulwe.
Ungathola amathiphu engeziwe okusebenzisa izithako lapha.
Lapho Uzokuthola
Etholakala kakhulu ukuthengwa ku-intanethi, ama-amino acids e-branched athengiswa ezitolo eziningi zokudla zemvelo nasezitolo ezikhethekile ezisekelweni zokudla.
Ukusebenzisa It for Health
Ngenxa yokucwaninga okulinganiselwe, kusheshe kakhulu ukutusa ama-amino acid we-branched njengokwelashwa kwanoma yisiphi isimo. Kubalulekile ukuphawula ukuthi ukuzitholela isimo nge-branched chain-chain amino acid, futhi ukugwema noma ukubambezela ukunakekelwa okujwayelekile, kungaba nemiphumela emibi. Uma ucabangela ukusetshenziswa kwe-amino acid e-branched-chain, qiniseka ukuthi ubonisana nomhlinzeki wakho wokunakekela oyinhloko ngaphambi kokuqala uhlelo lwakho lokufaka isicelo.
Imithombo
I-Bianchi G, i-Marzocchi R, i-Agostini F, i-Marchesini G. "Ukubuyekezwa kokuxhaswa okunomsoco nge-branino-chain amino acid." Ukwelashwa kweMetab we-Curr Opin Clin. 2005 Jan; 8 (1): 83-7.
Blomstrand E. "Indima ye-amino acids ye-branched-chain ekunciphiseni ukukhathala okuphakathi." J Nutriti. 2006 Feb; 136 (2): 544S-547S.
Blomstrand E, Eliasson J, Karlsson HK, Köhnke R. "Ukuhlanganiswa kwamakhemikhali amino acid kusebenze ama-enzyme ayisihluthulelo emaprotheni emva kokuzivocavoca umzimba." J Nutriti. 2006 Jan; 136 (1 Suppl): 269S-73S.
Higuchi N, Kato M, Miyazaki M, Tanaka M, Kohjima M, Ito T, Nakamuta M, Enjoji M, Kotoh K, Takayanagi R. "Indima ebalulekile ye-amino acids e-branino-chain in glucose metabolism ngokusebenzisa ukufakwa kwe-glucose- ukuzwa amadivaysi esibindi. " J Cell Biochem. 2011 Jan; 112 (1): 30-8.
Koba T, Hamada K, Sakurai M, Matsumoto K, Hayase H, Imaizumi K, Tsujimoto H, Mitsuzono R. "Ukuhlanganiswa kwe-amino acids supplementation kunqanda ukuqoqwa kwegazi lactate dehydrogenase ngesikhathi sokuhamba ibanga." J Sports Med Phys Ukufaneleka. 2007 Sep; 47 (3): 316-22.
I-Negro M, i-Giardina S, iMarzani B, i-Marzatico F. "Ukuhlanganiswa kwe-amino acid supplementation akukhulisi ukusebenza kwezemidlalo kodwa kuthinta ukubuyiswa kwemisipha kanye nesistimu yomzimba." J Sports Med Phys Ukufaneleka. 2008 Sep; 48 (3): 347-51.
Ukuziphendulela: Ulwazi oluqukethwe kule sayithi luhloswe ngezinjongo zemfundo kuphela futhi aluthathi iseluleko, ukuxilongwa noma ukwelashwa ngudokotela olayisensi. Akuhloselwe ukumboza zonke izinyathelo zokuqapha, ukusebenzisana kwezidakamizwa, izimo noma imiphumela emibi. Kufanele ufune ukunakekelwa okusheshayo kwezokwelapha kunoma yiziphi izinkinga zezempilo bese uthintana nodokotela wakho ngaphambi kokusebenzisa enye imithi noma wenze ushintsho ohlelweni lwakho.